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Finally, some commonly used drugs (e.g., glucocorticoids and GLP-1RAs) can also affect intra-portal insulin levels that modulate the GH/IGF-I axis either by increasing or decreasing hepatic GH sensitivity, as reflected by the discordant GH and IGF-I levels

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Were grateful for the opportunity to have meaningful conversations about the challenges and opportunities ahead, and even more grateful for leaders who continue to listen, lead, and advocate for our profession every day

10.1016/0024-3205(94)00796-9 119 SikiricP.SeiwerthS.GrabarevicZ.RucmanR.PetekM.JagicV.et al (1997c)

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Sparse clinical evidence versus real-world experience In a review of the evidence posted ahead of the meeting, they repeatedly note the data comes primarily from preclinical work involving animals and is quite limited for humans