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Warren SJ, Arteaga LA, Rivitti EA, Aoki V, Hans-Filho G, Qaqish BF, et al

Minimal discomfort and bruising at the insertion site can occur

Primary peptide: KPV at 200 to 400 mcg subcutaneously daily Support peptide: Thymosin alpha-1 at 1.6 mg subcutaneously twice weekly Implementation schedule: Pre-season (4 weeks before): Begin KPV daily and Ta1 twice weekly to stabilize mast cells and rebalance Th1/Th2 ratio before allergen exposure peaks During season: Continue both peptides at the same doses throughout the allergy season Post-season: Taper KPV over 2 weeks

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In the lung cell cultures, the peptide complex apparently reduced edema, inflammatory cell infiltration, and overall histologic injury scores