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Oxicam derivatives significantly impact macrophage-associated chemokine expression, which is crucial in colorectal cancer pathophysiology

On the other hand, studies exploring a possible association between cancer and extremely elevated vitamin B12 levels may understandably raise concerns

This leads to the accumulation of lactic acid

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For the tumour allograft model, Gclc f/f Rosa26 creERT2 MMTV-PYMT mice and control C57BL/6 mice (The Jackson Laboratory, 000664) were used (female, at least 12 weeks old)