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The nanocarrier simultaneously delivers siRNAs against two critical anti-apoptotic genes, MCL-1 and Survivinboth known to promote tumor survival and resistance to therapy
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By inhibiting drug-metabolizing enzymes (e.g., cytochrome P450, UDP-glucuronosyltransferase) and enhancing intestinal absorption (21, 32), PPR significantly inhibits P-glycoprotein (P-gp) and enhances the efficacy of co-administered compounds like CUR and RSV, positioning it as a critical adjunct in nutraceutical formulations (33, 34)
Titers were determined using the plaque assay described below
Carnitine--metabolism and functions
Moreover, the relationship between sperm midpiece size and mitochondrial sheath length is crucial for motility, as it determines the energy-generating capacity of sperm cells (Morita et al
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