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In addition, research has demonstrated that the activation of 7nAChR in microglia has the potential to elicit anti-inflammatory effects [27, 28]

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Mechanistically, ALC exerts its antidepressant effects via multiple pathways, including enhancement of mitochondrial function, upregulation of brain-derived neurotrophic factor (BDNF), modulation of glutamatergic neurotransmission, and epigenetic regulation of gene expression involved in mood regulation