Metabolic alterations, such as chronic hyperglycemia, insulin resistance, and increased metabolism of free fatty acids, result in oxidative stress, inflammation, advanced glycation end product formation, and abnormalities in calcium homeostasis, leading to apoptosis, fibrosis, and endothelial dysfunction [21], which represents the main initiating factor in the pathogenesis of diabetic vascular complications
6, A388A389
The European Journal of Clinical Nutrition highlighted the importance of protein intake for preserving bone health and preventing sarcopenia (age-related muscle loss) in individuals undergoing weight loss (3)
The rationale for lower-dose protocols Standard GLP-1 titration is associated with high rates of gastrointestinal side effects particularly nausea during dose escalation
doi: 10.3390/nu13062099, 13 ChiaranuntP.BurrowsK.NgaiL.TaiS
Are national telehealth providers available everywhere