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SGLT-2 Inhibitors: the gap Seems to Be Leveling off

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doi: 10.1590/s0102-865020190010000001 70 WannerC.InzucchiS

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GLP-1RAs have pleiotropic effects: they improve neurogenesis, reduce apoptosis, protect neurons from oxidative stress, and reduce neuroinflammation in various neurological conditions, and it is these beneficial effects that can be used in aging-related diseases, mainly AD and PD

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These symptoms can affect up to 30-45% of patients during dose escalation (varying by medication and dose) and can lead to significant fluid losses if not managed appropriately

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Can we prevent complications before they occur

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