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285 Multi-phenotype GWAS uncovers shared genetic loci between type 2 diabetes, colorectal, breast, and prostate cancers, leading to reclassification of risk loci A

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doi: 10.1016/j.tifs.2023.104211 27

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Mice lacking Mc4R are not responsive to lorcaserin-induced hypophagia, indicating that melanocortins acting on Mc4R are essential for altering food intake in response to 5-HT 2C receptor agonists [14, 134]