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While nuclear factor erythroid 2-related factor 2 (NRF2) and CCAAT/Enhancer Binding Protein (CEBP) also contribute to a minor increase in CHAC1 transcription, their roles are less pronounced compared to ATF4 ( FIGURE 4 ATF4 and ATF3 regulate CHAC1 expression by binding to specific sites within its promoter, the ATF/cAMP response element (CRE) at position 267 and the ATF/CRE modifier (ACM) motif at 248

In recent year they have become popular due to the benefits for muscle growth and physical recovery

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Antisense suppression of 2-cysteine peroxiredoxin in Arabidopsis specifically enhances the activities and expression of enzymes associated with ascorbate metabolism but not glutathione metabolism

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PeptiStrong also significantly suppressed plasma myostatin levels