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L-carnitine has been shown in preclinical studies to protect against kidney toxicity from cisplatin and ifosfamide (Sayed-Ahmed 2010

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Metabolome changes in lupus PBL reveal a dominant impact on the PPP that reflect greater demand for nucleotides and oxidative stress

May 2018;25(3):281-290

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The study addressed two questions: whether the fragment retained activity when delivered enterally rather than parenterally, and whether the effects observed in rodent models translated to human adipose tissue at the cellular level