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Studies show that patients who reduce their semaglutide dose slowly are more likely to maintain their weight loss than those who stop suddenly

This is associated with an increase in Alloprevotella and Bacteroides , and a decrease in Lachnospiraceae_NK4A136_group (Zhang Y

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Instead, a structured carbohydrate refeed temporarily increasing carbohydrate intake to maintenance level calories for one to two days can restore glycogen stores, normalize hunger hormones, and restore metabolic rate enough to resume fat loss progress

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