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Pediatric obesity: An overview of etiology and treatment

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Persistent mitochondrial ROS generation leads to lipid peroxidation, increased membrane permeability, mitochondrial uncoupling, and inflammatory signalling via tumor necrosis factor-alpha (TNF-), thereby perpetuating hepatocellular damage [55, 56]

The most powerful protocols combine targeted peptide therapy with bioidentical hormone replacement therapy (BHRT) addressing the root hormonal decline while simultaneously optimizing the downstream systems that hormones support

On top of that, to lower the chance of side effects, the treatment plan involves gradually increasing the dose from the lowest (0.25mg) to the highest (2.4mg)

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