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2A), and ITC purification alone was sufficient to isolate the dual agonist from contaminants

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This enzyme, which was considered to be expressed only in kidney, liver and brain, catalyzes the last step in the carnitine biosynthesis pathway

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We then envisioned two further scenarios that could explain the differential Nt 7 compartmentalization: (i) PATs have no specificity for substrate recognition, and substrates concentrate at different compartments due to specific interactions, and (ii) PATs discriminate substrates, which in turn accumulate at the compartment where S-palmitoylation takes place