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This isnt a failing of the medicines it reflects the nature of obesity as a chronic, relapsing condition, said Dr

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You need more than 12 weeks of support to get back to having a healthy relationship with food. Evidence from the STEP 1 extension trial suggests that once people stop taking semaglutide, they will put the weight back on[7]

Semaglutide is a GLP-1 receptor agonist developed initially to treat type 2 diabetes and later approved for chronic weight management

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For most people, the nausea is mild to moderate and improves as the body adjusts