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In a separate study involving 190 patients receiving 52 weeks of treatment, remission rates were 36.8%, 45.6%, and 52.0% for the 5, 10, and 15 mg tirzepatide groups, respectively, compared to 18.2% in the placebo group (Loomba et al., 2024)

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The VPA -oxidation metabolite 2-en-VPA is another agent that can promote cerebral oedema when it accumulates in brain and plasma

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