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Description

Mechanisms of cisplatin ototoxicity and progress in otoprotection

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Building on these findings, recent research has highlighted [5] the remarkable therapeutic potential of BPC-157 in humans

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In humans, the CYP450 enzyme that predominately catalyses the formation of NAPQI is CYP2E1, although in vitro CYP3A4, CYP2D6 and CYP1A2 have also been implicated in the formation of the toxic metabolite [18,19,20]

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