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Using data from three clinical trials that included 1,119 participants with diabetes, researchers found that people carrying PAM variants generally responded less well to GLP-1 receptor agonists

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Most studies rely on single-parameter assessments, and a comprehensive model linking SIRT1 activation efficiency with phenotypic improvement is lacking

Eliapixant is a selective P2X3 receptor antagonist for the treatment of disorders associated with hypersensitive nerve fibers

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