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In WT mice, both AOD9604 and hGH elevated plasma glycerol levels, indicating enhanced lipolytic activity

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However, the results showed that the overall effect size depended on some studies with respect to IL-6 (Reference Kondori, Ghaleh and Hosseini35) and SOD (Reference El-Elimat, Qasem and Al-Sawalha34,Reference Venkatakrishnan, Chiu and Cheng41,Reference Maeda-Yamamoto, Nishimura and Kitaichi43,Reference van het Hof, de Boer, Wiseman, Lien, Westrate and Tijburg68)

However, the simple model (OR, 1.017,95% CI, 0.9271.116, P = 0.723) demonstrated causal effects that were directionally consistent but not statistically significant