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This transcriptional profile during CI dysfunction suggests a broader impairment in adipocyte metabolism and function, extending beyond isolated electron transport chain (ETC) disruption

While Saxenda is generally well tolerated, it is associated with a range of potential side effects, most commonly gastrointestinal symptoms such as nausea, diarrhoea, constipation, and vomiting

We clustered the cells using shared nearest neighbor graph construction and the first ten principal components, yielding 16 clusters (Methods and Extended Data Fig

Similarly, numerous investigations into diabetic cell targets have indicated that increasing Nrf2 levels safeguards against ferroptosis, thereby mitigating organ damage

10.1210/endo.133.6.8243312 Endocrinology 38 VejrazkovaD.LischkovaO.VankovaM.StanickaS.VrbikovaJ.LukasovaP.et al (2017)

Increased serum transferrin receptor concentrations in Friedreich ataxia