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(STEP-1 Trial, NEJM 2021) (Prescriber NICE TA875 Summary) If your side effects are still significant after 4 weeks on a particular dose, speak to your doctor or pharmacist

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Monitor weight, glycaemic control and side effects

Patients should be educated about red flag symptoms that require urgent assessment

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Taking L-Carnitine in the morning can also be effective, especially if you prefer to take your supplement first thing