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More than half of those without preexisting conditions said they drank less alcohol when taking a GLP-1

These findings translate to clinical research, as increased insulin resistance in patients with PD has been related to the severity of non-motor symptoms [155]

Although there are many ongoing large CVD outcome trials of GLP-1 RA treatment (Table 1), more simultaneous investigation of the causal relationship between GLP-1 RA administration and useful surrogate measures of CVD, including carotid IMT, would help us understand the potential mechanisms through which GLP-1 RAs may result in favorable cardiovascular outcomes in patients with T2D

The GLP-1 analog semaglutide showed similar results in mice by a dose-dependent reduction in binge drinking via the probable mechanism of modulating GABA neurotransmission centrally

GLP-1 medications are generally well-tolerated, but they do come with a side effect profile, which is worth understanding before starting treatment

Thats why a broader medical assessment is usually carried out