Neurological and muscular disturbances (motor disturbances, convulsions, and excessive fatigue (weakness)) and laboratory tests (increased or decreased concentration of different biochemical markers in tissues, blood, and urine) can indicate mitochondrial damage [26,35]
Plants 12:3937
10.3390/antiox13121567 [DOI] [PMC free article] [PubMed] [Google Scholar] Arenas-Jal M., Su-Negre J
Additionally, metformin effectively alleviates oxidative stress-mediated neurotoxicity by upregulating LONP1 expression in the brains of streptozotocin-induced diabetic mice [93]
We excluded off-topic articles and studies with insufficient methodological detail (missing model/species, dose, route, duration, controls)
Vitamin B12 is a water-soluble vitamin thats naturally found in animal foods and products - particularly shellfish, meat, eggs, and dairy products