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While semaglutide offers superior results, it is not without potential side effects, such as gastrointestinal discomfort, and may not be suitable or accessible for everyone

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And Saxenda really helped there

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Standard dosing and titration schedules are often suitable across most CKD stages because these medications are not primarily metabolized by the kidneys , meaning reduced kidney function has minimal impact on how the body processes them

weekly for semaglutide, dulaglutide, and tirzepatide) and following dose escalation schedules carefully can reduce the intensity of gastrointestinal side effects that contribute to taste changes