Different mechanisms of action Mounjaro works differently from Wegovy when it comes to how it helps with weight loss and blood sugar control
A., Dalbge, L
[DOI] [PMC free article] [PubMed] [Google Scholar] 107.Wen X., Ding Y., Li J., Zhao J., Peng R., Li D., Zhu B., Wang Y., Zhang X., Zhang X
This is particularly important if you take any diabetes medications like insulin or sulfonylureas, as using Wegovy alongside them can increase your risk of hypoglycaemia
Maintain or increase exercise volume
This effect is likely driven by the prolonged circulating half-lives of long-acting and ultra-long-acting GLP-1RAs, such as semaglutide (via fatty acid acylation) and dulaglutide (via Fc fragment fusion), which maintain sustained GLP-1 receptor stimulation and enhance intestinal motility, thereby increasing diarrhea risk