(DOC) Author Contributions Conceived and designed the experiments: SL QL HT XS
Concomitant pharmacological treatments, particularly metformin, further complicate interpretation due to their documented microbiota-modulating effects
Important handling instructions include: remove the needle after each use, do not store with the needle attached, do not share pens with others, keep the pen cap on when not in use, visually check that the solution is clear and colorless before injection, and keep out of reach of children
These effects can lead to damage to cells and tissues, further burdening the liver and other organs involved in detoxification
Most "research" vendors do not maintain cold-chain shipping, and most landing pages do not disclose this
Lastly, although the hangover symptom surveys (AHS and AHSS) showed no significant differences between the GSH and placebo groups overall, the subjective nature of these surveys may have influenced the results