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Berberine regulates gut microbiota, increases beneficial bacteria, decreases harmful bacteria, and enhances the gut barrier, thereby reducing LPS translocation and its mediated TLR4/NF-B pathway activation to inhibit liver inflammation

404,405 A recent study demonstrated that siRNA conjugated to cyclic RGD (cRGD) could selectively enter cells that express v 3 integrin

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Look for co-factors like Selenium and Vitamin C

Both tocilizumab and satralizumab are being evaluated in gMG therapy (NCT05067348 and NCT04963270)