glp-1 doesn't work for me 7 Reasons You Aren't Losing Weight on Weight Loss Drugs GLP-1s Don't Work for Everyone:

Potential mechanisms of Shu Gan Jie Yu Capsule in the treatment of mild to moderate depression based on systemic pharmacology and current evidence

Studies suggest that GLP-1 activation can influence microglial cells, which play a role in neuroinflammatory responses

Men, muscles, and eating disorders

For optimal results, combine both approaches

in tandem with other human factors such as the human leukocyte antigen (HLA), epigenetics, preexisting comorbidities (i.e., T2DM, CVD, obesity), age, preceding systemic impairments (i.e., hyperinflammation, micro-thrombosis, fibrosis, dysbiosis, autoimmunity, etc.), and socio-demographic factors (i.e., food security, environment, access to medical care) 22,27,28

These are not interchangeable drugs they have overlapping but distinct mechanisms