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When the financial burden is lower, patients are more likely to maintain regular doses without skipping or delaying refills

The percentage of patients who discontinued for lack of glycemic control or who were rescued for meeting prespecified glycemic criteria was 16% in the saxagliptin 2.5 mg treatment group, 20% in the saxagliptin 5 mg treatment group, and 26% in the placebo group

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Preclinical studies suggest that DSIP may affect the balance between wakefulness and sleep, as well as responses to stress and pain perception