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Dose ladder 2.5 5 7.5 10 12.5 15 mg weekly, with at least 4 weeks between steps

It is used in "Phase II" detoxification, where it binds to toxins to make them water-soluble so they can be filtered out of the body

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As an illustration, investigations into the impact of 1-methyl-4-phenylpyridinium (MPP+), known for its neurotoxic effects mediated by various mechanisms, including complex I (CI) inhibition, demonstrated elevated glutathione (GSH) levels coupled with the upregulation of ATF-4 and the transsulfuration enzymes CTH and CBS

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