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The proportions of patients who discontinued study drug in Study 2 were 9.3% and 13.8% for the 10 mg and 15 mg ZEPBOUND-treated groups, respectively, and 14.9% for the placebo-treated group

They work by drawing water into the colon and are gentler than stimulant laxatives

Functional Significance of the Excitatory Effects of GABA in the Suprachiasmatic Nucleus. Journal of Biological Rhythms, vol

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