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In particular, we focused on the p21 N-terminal cyclin-CDK binding domain, required for inhibition of G1/S cell cycle progression, and the C-terminal PCNA binding domain involved in suppressing DNA synthesis (Chen et al, 1995) (Fig 2D)

Thus, inhibition of the VCP-UFD1-NPLOC4 pathway may represent as a selective treatment option for cancer

The most common side effects remain mild and localized, primarily involving injection site reactions that resolve spontaneously

Recent studies have uncovered a fascinating aspect of the VEGF, shedding light on its multifaceted involvement in neurodegeneration, a domain previously less explored

Floriculture, Ornamental and Plant Biotechnology