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Although the overall clinical sample is large, the Recent and Established groups were designed to have half the number of controls (n = 30) as patients (n = 60) to increase the power of within-patient analyses but at the cost of power for control- patient comparisons

Additionally, the time required to complete the enzymatic activity measurements was prolonged, and the method needed to be more easily adaptable to microplate readers due to the necessity of protein precipitation

Acetaldehyde disrupts tight junctions and adherens junctions in human colonic mucosa: protection by EGF and L-glutamine

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10.1124/MOL.65.2.335 42 DanC.JinjunB.ZiChunH.LinM.WeiC.XuZ.et al (2015)

These findings warrant medical review before adding supplements