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Appl Environ Microbiol 69(11):68646874 Reinhold-Hurek B, Bnger W, Burbano CS, Sabale M, Hurek T (2015) Roots shaping their microbiome: global hotspots for microbial activity

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Hemibiotrophic Fungi The important role of GSTs in antifungal plant resistance was demonstrated also in hemibiotrophic plant-fungus interactions

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G6PD deficiency reduces the amount of NADPH, which is required for the formation of nitric oxide (NO) [10, 11]

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For example, homocysteine (Hcy), an amino acid involved in DNA methylation, facilitates GPX4 methylation that leads to upregulation of oxidative stress and ferroptosis in nucleus pulposus (Zhang et al., 2020c)

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Notably, lactate-primed lysine acetyltransferase 8 directly lactylates mitochondrial phosphoenolpyruvate carboxykinase 2 at K100, thereby enhancing its kinase activity and reprogramming mitochondrial fatty-acid synthesis to promote ferroptotic processes (118)

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Week 4 to 8: the escalation peak This is typically the worst period

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