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Studies have shown that in contrast to melanoma of nongenital sites, which has a peak incidence in early to middle adulthood, vulvar melanoma has its peak incidence around the sixth decade of life

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Zhu Y, Meng Y, Zhang J, Liu R, Shen S, Gu L, et al

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After adjusting for insulin resistance, the differences in GLP-1 sensitivity between lean and obese subjects were no longer significant, suggesting that its effects are modulated by the individuals insulin sensitivity status