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Using degraded medication may result in: Suboptimal blood glucose control in patients with type 2 diabetes Reduced weight loss efficacy for those using GLP-1 agonists for weight management Unpredictable dosing , as degradation may be partial rather than complete Patients with diabetes who suspect reduced medication efficacy should monitor their blood glucose more frequently and contact their GP or diabetes care team if they have concerns about medication storage or if their diabetes control deteriorates unexpectedly

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The combination can lead to rapid fluid depletion, worsening the dizziness, headaches, and fatigue already common during early GLP-1 therapy