Weight regain after stopping semaglutide or tirzepatide
GLP-1 users are more active and feel better Americans who have been using GLP-1 medication for weight loss have found that theyre more active in life (42%), with exercise (41%), and sexually (29%)
The Bigger Concern: Appetite Suppression During Lactation While medication transfer appears minimal, GLP-1 medications are designed to reduce appetite and slow digestion
[24] This becomes especially valuable during caloric deficits, where every gram of protein counts
However, their capacity to cross the BBB varies substantially across compounds and is influenced by a combination of molecular weight, hydrophilicity, protein binding, susceptibility to enzymatic degradation, and structural modifications [66]
doi: 10.1186/s13722-025-00618-2, 42 FriedrichsenM.BreitschaftA.TadayonS.WizertA.SkovgaardD