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Several GLP-1RAs CVOTs included patients with chronic kidney disease and showed consistent cardiovascular and some renal benefits

Thus, GLP-1 and GLP-1RAs have a beneficial effect on neurogenesis, potentially having translational significance, since these compounds can have a positive effect in various mental disorders characterized by defects in neurogenesis (including depressive disorders and neurocognitive disorders)

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Thus, it is not surprising that GSH (or the [GSH]/[GSSG] ratio) plays a key role in many diseases including cancer, inflammation, Alzheimer's disease, Parkinson's disease, sickle cell anemia, liver disease, cystic fibrosis, AIDS, heart attack, stroke, and diabetes [4, 6] as well as in aging [79]