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Kidney problems : Risk of kidney injury due to dehydration from nausea, vomiting, and diarrhea

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Tirzepatide produced greater average weight and waist reduction, while gastrointestinal adverse events were most common with both medications and were generally mild to moderate

While they may cause modest increases in heart rate (typically 2-4 beats per minute) and modest decreases in blood pressure, they do not significantly raise core body temperature or substantially accelerate metabolic rate

It summarizes the technical point description of the patent document