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Constipation: A less common but still notable side effect

The litigation remains focused on product defect claims and failure to warn

adults live with obesity, according to the CDC, and many patients exploring treatment options face a fragmented process coordinating provider visits, prescription access, lifestyle changes and insurance considerations across multiple sources

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The receptor itself couples to multiple G proteins (Gq/11, Gi/o, G12/13, and -arrestin), and different agonists can bias signaling toward different pathways (Overlapping binding site study, 2008)

6 Given their high prevalence among the general population, they may pose a potential economic problem as well