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In vitro studies using endothelial cell models have demonstrated effects on fibroblast migration rates, endothelial cell tube formation in angiogenesis assays, and cytoprotective mechanisms in cell culture models exposed to oxidative and chemical stressors
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Relaxin-2, a peptide hormone, has demonstrated the ability to restore range of motion and eliminate capsular fibrosis in mouse models of shoulder arthrofibrosis, making it perhaps the most specifically relevant peptide for this condition
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Subjects ( N = 14) were randomized to either a supplement (R + MSM) or a control group using an open label design
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