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Clinical assessment and full blood count showing macrocytic anaemia are also important, though neurological symptoms can occur without haematological changes

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NIDDK lists orlistat (Xenical, Alli), phentermine-topiramate (Qsymia), naltrexone-bupropion (Contrave), liraglutide (Saxenda), semaglutide (Wegovy), and tirzepatide (Zepbound) for long-term use, along with setmelanotide (Imcivree) for certain rare genetic causes of obesity

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