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The pituitary gland releases GH in pulses, and that release is gated by two independent controls: a go signal from GHRH and a separate go signal from the ghrelin/GH-secretagogue receptor

127129 Telomere attrition The gradual reduction of telomeres as we grow older is a significant characteristic of aging, leading to cellular senescence and impairing tissue function

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Lancet 370 , 504510 (2007)

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