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As the condition persists or worsens, increasing symptoms such as abdominal or chest pains can develop

Suggested Dosage and Directions: Capsule: Take 1 capsule with water

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A total of 539 patients were enrolled with 359 patients randomized to pemetrexed and 180 patients randomized to placebo

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AUTHORS CONTRIBUTIONS Daria Abasheva made substantial contributions in the design of the work, bibliographic research, interpretation and drafted the manuscript, contribute to text and contents of the manuscript including revisions and edits and approve of the content of the manuscript and agree to be held accountable for the work