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Here's how Semaglutide works: Appetite Regulation: Semaglutide helps regulate appetite by acting on the brain's appetite control centers, making you feel full and satisfied with smaller meals

Potentially severe side effects of Trulicity: Hypoglycemia Gastroparesis (stomach paralysis) Ileus (intestinal blockage) Gallbladder disease Kidney damage Pancreatitis Thyroid tumors (Trulicity carries a boxed warning of thyroid tumors after studies showed an increased risk in animals, but had unclear implications for humans) Allergic reactions Signs and symptoms of serious side effects may include severe abdominal pain, persistent nausea, vomiting, fever, dark urine, or signs of an allergic reaction

JAMA Pediatr 2014;168:7218

Common side effects include nausea, diarrhea, decreased appetite, vomiting, and constipation, which are usually mild and diminish over time

Chiappetta S, Stier C

The peptide effectively reversed the muscle strength decrease caused by glucocorticoid treatment