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Asian J Psychiatry

BMPs regulate NSC differentiation into astrocytes by acting through the phosphorylation of Smad proteins 1, 5, and 8, which combine with Smad4 in order to form a complex that translocates to the nucleus and regulates gene transcription (Itoh et al., 2000

The formulations designed for oral absorption (arginine salts, absorption enhancers) are attempting to solve this problem, but we dont have human pharmacokinetic studies proving how much actually gets absorbed

[DOI] [PubMed] [Google Scholar] 41.Gottfried C., Bambini-Junior V., Francis F., Riesgo R., Savino W