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The compound's procognitive effects stem from its ability to enhance synaptogenesisthe formation of new functional synapses between neuronsparticularly in the hippocampus, a brain region essential for learning and memory consolidation
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The clinical translation of these trial results, which will be important for the comparison of GLP-1RAs with SGLT2 inhibitors in the treatment of patients with heart failure and a preserved ejection fraction, remains to be determined
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229 In another randomized, double-blind, placebo-controlled trial of 300 people with high cholesterol levels and at high risk of cardiovascular disease, subjects were randomized to receive either 180 mg of bempedoic acid, 10 mg of ezetimibe (which prevents the intestinal absorption of cholesterol), a combination of the two medications (180 mg of bempedoic acid and 10 mg of ezetimibe), or placebo in addition to stable statin therapy for 12 weeks
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US$ 20.14
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