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72 For example, the elimination rate constant of theophylline is less in cats (0.089/hr) 73 than dogs (0.12/hr), resulting in a longer half-life in the cat (7.8 hours) compared with the dog (5.7 hours), 64, 65 thus necessitating a smaller dose in cats

Patients with GLP1R variants (rs6923761) demonstrate variable receptor expression, correlating with tirzepatide dose requirements and nutrient depletion rates

Both of these conditions are rare

Wu, X.-H

We connected RK-33 to cereblon (CRBN) ligand thalidomide, generating PROTAC DDX3X degraders with linker arms of varying lengths for the investigation of DDX3X protein-degrading activity and antitumor efficacy

On the other hand, M2 macrophages are known for their role in exerting anti-inflammatory and immunosuppressive effects, which they achieve by producing anti-inflammatory cytokines like IL-10