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In one, Trump says there will be a 90-day hiring freeze for the federal government, with the directive to reduce the size of the federal workforce when the order expires

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46,47 Nevertheless, the FDA requires GLP-1 receptor agonists to carry a black-box warning regarding the risk of thyroid C-cell tumors, and it recommends against using them in patients with a personal or family history of medullary thyroid cell cancer or multiple endocrine neoplasia syndrome type 2a or 2b