Hyperactivity in the dorsal cochlear nucleus after intense sound exposure and its resemblance to tone-evoked activity: A physiological model for tinnitus
At high, fixed pharmacological doses it measurably reduces peripheral insulin sensitivity
This pulse and sustain pattern minimizes the risk of desensitization or overexposure, supporting consistent performance and recovery outcomes
Recent work has also suggested a larger role for innate immunity in SJS/TEN pathogenesis, beyond the involvement of NK cells, monocytes, and macrophages
Cell Pathol
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