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10.1007/978-3-030-30402-7_7 99 MargedariP.GoudarziI.SepehriH

GH acts on target tissues mainly via stimulation of the somatomedin insulin-like growth factor-1 (IGF-1, 7.6 kDa), and to a lesser extent, directly in an IGF-1 independent manner

Results: Of 382 participants (median: age 75, NIHSS 6, symptom onset to test 130 mins), 290 had complete data for analyses (after removal of void test results and ischaemic stroke without CTA/MRA)

By age 60, levels of healing peptides like GHK-Cu drop to about 40% of what they were at age 20

The cellular signaling cascade it initiates requires time to propagate, and the 5-day gap is recovery time at the mitochondrial level